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TriKE Technology Sparks OXIS International, Inc. (OTCMKTS:OXIS)

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OXIS International, Inc. (OTCMKTS:OXIS) got a recent boost in volume and price after the Company announced it has entered into an agreement with the University of Minnesota to develop and commercialize cancer therapies using Trispecific Killer Engager (TriKE) technology developed by researchers at the university to target NK cells to cancer.

OXIS has been trading strong as the Company adds new patients to their Phase 1/Phase 2 trial of its most promising cancer drug, OXS-1550. Late last year OXIS received notification from the FDA that they can proceed with their planned combination Phase 1/Phase 2 clinical trial for OXS-1550.

OXIS International, Inc. (OTCMKTS:OXIS) is a biotech company that develops and commercializes innovative drugs of therapeutic molecules including cannabinoids, which are focused on several cancer indications. Oxis address the clinical shortcomings of existing commercial products in related fields. OXIS has formed relationships with some of the world’s leading cannabinoid researchers and institutions to advance its technologies.

The Company has Tony Cataldo behind it who recently said ”As the founder of Lion Biotechnologies, Inc. (LBIO $240 Million market capitalization) I found the same dynamics when creating the nucleus for markets in cell therapies, which brought significant market cap appreciation in exploding biotech sectors. They are now present in the Cannabinoid/Medical Marijuana sector for Oxis Biotech, Inc. to take advantage of.

In September OXIS announced the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

DT2219ARL is a bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. CD19 is a membrane glycoprotein present on the surface of all stages of B lymphocyte development, and is also expressed on most B-cell mature lymphoma cells and leukemia cells.1 CD22 is a glycoprotein expressed on B-lineage lymphoid precursors, including precursor B acute lymphoblastic leukemia, and often is co-expressed with CD19 on mature B-cell malignancies such as lymphoma.2

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On November 23 OXIS announced its collaborators at the University of Minnesota Masonic Cancer Center received notification from the U.S. Food and Drug Administration (FDA) that they can proceed with their planned combination Phase 1/Phase 2 clinical trial for OXS-1550. Oxis holds worldwide exclusive rights to develop and commercialize OXS-1550, a novel therapy for the treatment of leukemia and lymphoma.

OXS-1550 targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When OXS-1550 binds to cancer cells, they internalize OXS-1550 and are killed due to the action of drug’s cytotoxic payload. OXS-1550 has demonstrated success in early human clinical trials in patients with B-cell lymphoma or leukemia.

In June OXIS said it has begun enrolling patients in a Phase 1/Phase 2 trial of its most promising cancer drug, OXS-1550. The FDA-approved clinical trial is being conducted at the University of Minnesota’s Masonic Cancer Center under the watch of Dr. Daniel Vallera, a research scientist who developed the drug and is a member of the Scientific Advisory Board of Oxis’ wholly owned subsidiary, Oxis Biotech Inc.

On July 25 OXIS announced its wholly owned subsidiary, Oxis Biotech Inc., has entered into an agreement with the University of Minnesota to develop and commercialize cancer therapies using Trispecific Killer Engager (TriKE) technology developed by researchers at the university to target NK cells to cancer.

CEO Anthony J. Cataldo said the new agreement provides the company with a significant asset. He said TriKE technology is important because it’s highly effective at killing cancer cells with minimal side effects in pre-clinical models.

“The bispecific antibody platform is well known for its ability to kill cancer cells via antibody dependent cell-mediated toxicity (ADCC). However, current successes in immunotherapy indicate that enhanced killing will not be enough. We believe the TriKE platform from University of Minnesota has found a way to expand the immune cell population within the patient, but not at the expense of creating a toxic environment.”

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Currently trading at a $6.5 million market valuation OXIS has minimal assets or revenues and significant rising short term debt. At the same time OXIS is an exciting story developing in small caps that just announced it has added 6 new patients in a Phase 1/Phase 2 trial of its most promising cancer drug, OXS-1550. Oxis holds worldwide exclusive rights to develop and commercialize OXS-1550. OXIS has a long way to go with Tony Cataldo as CEO and the Company up listing to the OTCBB. Mr. Cataldo has employed the same strategy he used as founder of LBIO and speculators seem to love the news with OXIS quickly gaining a loyal shareholder base that swears this one goes way higher.We will be updating on OXIS when more details emerge so make sure you are subscribed to Microcapdaily so you know what’s going on with OXIS.

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Disclosure: we hold no position in OXIS either long or short and we have not been compensated for this article.

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Solowin Holdings (NASDAQ: SWIN) 95% Stock Rally: Analyzing the Market Hype and IPO Impact”

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  • Solowin Holdings (NASDAQ: SWIN) has been making headlines this week, with its stock price soaring by an impressive 94% since Monday, September 18th, 2023. This surge follows the company’s announcement of their IPO on September 6th, 2023. Despite the lack of recent filings or news updates, the stock continues to experience significant gains, and the trading frenzy shows no signs of slowing down. It’s a puzzling situation, and if you’re following this, you might be feeling a bit bewildered. Interestingly, this kind of rapid and exaggerated performance is not necessarily unusual. We’ve seen similar behaviour with others last summer, AMTD Digital (NYSE: HDK) and Top Ships (NASDAQ: TOPS) to name a couple.

About Solowin Holdings:

Before we get into what’s happening and why, here’s a little background on the company based on the prospectus and “About” section in their latest press releases.

Solowin Holdings is a Hong Kong-based brokerage firm focused on Chinese investors. They offer a wide range of financial products and services through a secure and user-friendly online platform. They are licensed by the Hong Kong Securities and Futures Commission for various services. Their platform provides access to over 10,000 securities and their derivatives on major exchanges like HKSE, NYSE, Nasdaq, Shanghai Stock Exchange, and Shenzhen Stock Exchange. The company is known for its financial strength and technical expertise, serving both individual and institutional investors in Hong Kong and earning recognition from users and industry experts.

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It’s important to note that Solowin is not an operating company, but a Cayman Islands holding company with operations solely conducted by its subsidiary, Solomon JFZ (Asia) Holdings Limited, a limited liability corporation incorporated in Hong Kong.

Does it sound kind of fishy? Maybe… But is that enough to stop you from making a trade based off the intense retail hype we’re seeing during after hours trading on September 21, 2023? We’ll let you decide, but as per usual, always do your own due diligence. Stocks like these could cost you, and come with a significant amount of risk.

Thoughts from Retail:

Upon our initial research, the first thing we noticed was a notable user off Twitter, “MayaTrades” who started talking about the company’s potential earlier this week.

The user has since spoken on multiple occasions about the potential short squeeze the stock offers and suggests that it could continue to trade parabolically tomorrow on September 22nd, 2023. So it could be worth keeping an eye on to track the technicals.

We stumbled upon another user’s testimonial praising Maya’s day trading approach, claiming they’ve made over $15,000 using it. However, it’s essential to keep in mind that such testimonials endorsing various trading strategies are abundant on Twitter. It’s wise to approach these claims cautiously and form your own conclusions based on thorough research and analysis.

The general idea is that the shorts on SWIN are quite substantial, according to one user off Twitter, it’s 150% of the entire float and the stock hasn’t even seen the start of the squeeze yet. If it’s already gained over 90% in four days, I’m sure you can do the math on what this user is suggesting could happen next.

“Spec play that I have a lotto sized position in. It’s China. Cashed up for 5 years, allegedly. 2M float / 14M OS. I believe insiders will run it at some point, so whether it’s weeks or months, I’m holding a small position as it mirrors the other crazy China IPO runners. Currently $2.65” stated MayaTrades on September 14th, 2023.

We’re continuing to see the narrative of “No reason to close position with the strength SWIN is seeing into close” and that it’s seen “Unbelievable strength in a bloody market”. If you look at the technicals, you can see that it flagged into close yesterday and continued with the same pattern today.

Many also believe that the company has not only overcome previous resistance levels, but also surged beyond expectations in after hours trading September 21st, 2023. The stock just recently surpassed the $5 mark, leaving the future trajectory in the upcoming trading days quite unpredictable. This rapid movement follows a trend of consistently breaking through crucial resistance levels.

Once again, it’s important to acknowledge the speculative nature of these trades, with the possibility of a complete loss of investment. However, given the heightened retail interest surrounding the stock this week, we found it relevant to take note, delving into the factors and conversations driving this wave of excitement.

Short Squeeze:

By now, it’s safe to assume that most people are familiar with the concept of a short squeeze. We’ve covered it in several previous articles. However, if you’re new to the market or unfamiliar with our daily articles, here’s a brief explanation below:

A short squeeze is a market phenomenon where the price of a stock or other asset increases rapidly and significantly. This can be triggered by a surge in demand for the asset, often caused by a large number of investors who had bet against the asset (short sellers) rushing to buy it to cover their positions and limit their losses.

Short Selling: Short selling is a trading strategy where an investor borrows shares of a stock from a broker and sells them on the market, anticipating that the stock’s price will decline.

Betting Against the Stock: Short sellers profit when the stock price falls. They aim to buy back the shares at a lower price later to return them to the lender (broker), pocketing the difference.

Potential Losses and Squeeze: However, if the stock price starts to rise instead of fall, short sellers face potential losses. As the price climbs, they may feel pressured to buy the shares back to cut their losses, adding to the buying pressure in the market.

Buying to Cover: To exit their short positions, short sellers buy shares (covering their shorts) on the open market. This buying activity further drives up the stock price, as demand increases.

Feedback Loop: As the stock price rises due to increased buying from short sellers trying to cover their positions, it can trigger more short sellers to cover, creating a feedback loop of buying and price escalation.

Rapid Price Increase: The sudden increase in demand can lead to a sharp and swift rise in the stock price, catching short sellers off guard and forcing them to buy at higher prices to close their positions.

Magnitude and Duration: The extent and duration of a short squeeze can vary. It could be a short-lived spike or a more prolonged increase in the stock price, depending on the level of short interest, overall market conditions, and the availability of shares for shorting.

Short squeezes often attract significant attention and can result in substantial gains for those holding long positions, while causing substantial losses to short sellers, further fueling the market dynamics.

We will update you on SWIN when more details emerge, subscribe to Microcapdaily to follow along!

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Disclosure: We have not been compensated for this article/video. MicroCap Daily is not an investment advisor; this article/video does not provide investment advice. Always do your research, make your own investment decisions, or consult with your nearest financial advisor. This article/video is not a solicitation or recommendation to buy, sell, or hold securities. This article/video is our opinion, is meant for informational and educational purposes only, and does not provide investment advice. Past performance is not indicative of future performance.

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Advancing Medical Frontiers: Elutia Inc.’s(NASDAQ: ELUT) Strategic Vision in a $600 Million Market

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Elutia Inc (NASDAQ: ELUT) shares bolstered a whopping 33% today as the company recently shared that they’ve secured about $10.5 million in funding through a private investment round. If all the warrants are cashed in as part of this funding, the total could go up to $26.2 million.

Latest Changes:

Just last week, Aziyo Biologics changed its name to Elutia Inc. Following this change, Elutia made an announcement about selling its Orthobiologics business unit to Berkeley Biologics, a subsidiary of GNI Group Ltd. This move is set to bring in a substantial amount of cash, totalling up to $35 million for Elutia. This sum includes a notable upfront payment of $15 million, plus additional potential earnings of up to $20 million over five years. The deal is expected to be finalized in the fourth quarter of 2023.

This sale is a big step for Elutia, especially in the realm of drug-eluting biomatrix technology (DEB). Elutia is actively seeking approval from the FDA for their main product, CanGaroo RM. This product utilizes innovative biomatrix technology with antibiotics rifampin and minocycline (RM), providing long-term protection for cardiac pacemakers and defibrillators. This tackles a huge market estimated to be worth around 600 million. Elutia is aiming to introduce CanGaroo RM to the market in the first half of 2024.

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Standard Of Care:

Medtronic (NYSE: MDT) stands as the exclusive provider of the antibiotic envelope within the current market. This envelope is crafted using synthetic mesh infused with antibiotics. Back in 2014, Medtronic acquired this technology, making a strategic investment of up to $200 million. Primarily intended for Cardiac Implantable Electronic Device (CIED) revision procedures, this product boasts estimated annual sales in the range of $250 to $300 million.

However, despite its market presence and revenue generation, the Medtronic antibiotic envelope has notable limitations. While it effectively combats infections, its synthetic composition renders it less effective in supporting wound healing. Moreover, it poses challenges in accommodating larger devices like Subcutaneous Implantable Defibrillators (SCID).

Drug-eluting biomatrix (DEB):

Drug-eluting biomatrix (DEB) involves a specialized approach to drug delivery using a biomatrix as a carrier or platform. In simple terms, it’s a technique where a biomaterial matrix, often a biocompatible polymer or similar substance, is used to release drugs in a controlled and targeted manner.

The biomatrix acts as a support structure that can hold and gradually release drugs or therapeutic agents at a specific site in the body, typically over an extended period. This is particularly useful in medical applications where a localized and sustained delivery of medication is necessary.

For instance, in the context of Elutia’s CanGaroo RM, a biomatrix incorporating antibiotics rifampin and minocycline is used to provide prolonged protection for cardiac pacemakers and defibrillators. The biomatrix slowly releases these antibiotics at the surgical site, preventing infections and promoting healing.

DEB technology is gaining traction because it enhances treatment efficiency by ensuring the drug is delivered directly to the target area, minimizing side effects, and optimizing therapeutic outcomes. It’s a promising approach in the field of medical advancements, especially in areas like cardiology, oncology, and orthopedics.

Post-mastectomy Breast Reconstruction:

On top of this, the company also has plans to develop an RM version of its SimpliDerm biomatrix tailored for breast reconstruction procedures. The rate of infections after this surgery is quite high, more than 10%, highlighting a big medical need in a market valued at over $500 million. Elutia is stepping up to address this issue by developing SimpliDerm® RM, which incorporates their unique DEB technology. The funds raised through the private investment round (PIPE) and the sale of the Orthobiologics business unit will not only boost Elutia’s efforts in advancing their drug-eluting biomatrix products for the cardiac pacemaker and defibrillator market, but also for post-mastectomy breast reconstruction.

What’s next:

As mentioned earlier, their biomatrix platform serves two major markets. CanGaroo RM, their upcoming product, is slated for a 1H of 2024 market release and is poised to be a pioneer in a $600 million market. Furthermore, their SimpliDerm RM product utilizes the same proprietary antibiotic-eluting technology found in CanGaroo RM, which serves a 1.6B market according to their presentation deck. They aim to secure an IDE by Q4 2024, and upon achieving these milestones, they plan to venture into neurostimulator markets, particularly in pain management, to further drive their growth.

We will update you on ELUT when more details emerge, subscribe to Microcapdaily to follow along!

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Disclosure: We have not been compensated for this article/video. MicroCap Daily is not an investment advisor; this article/video does not provide investment advice. Always do your research, make your own investment decisions, or consult with your nearest financial advisor. This article/video is not a solicitation or recommendation to buy, sell, or hold securities. This article/video is our opinion, is meant for informational and educational purposes only, and does not provide investment advice. Past performance is not indicative of future performance.

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FingerMotion, Inc. (NASDAQ: FNGR): A Closer Look at its 500% Surge

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FingerMotion, Inc. (NASDAQ: FNGR) continues to gain traction in recent months,  gaining over 500% since June 9th, 2023 this year. If you’re reading this now, you’re likely eager to understand the reasoning behind it. Based on their latest announcements, there are no dramatic changes fundamentally to warrant such price action. Yet their stock continues on a significant upward trend. From what we’ve seen, it appears to be the force of retail investors banding together to combat against manipulation, potentially creating the ultimate short squeeze.

Thoughts from Retail:

As per retail investors and a notable Twitter user known as HAMShortkiller, there is widespread concern regarding potential manipulation within FingerMotion. The chair of the U.S. securities stock exchange, Gary Gensler, is facing increasing criticism from investors who assert that the SEC tends to overlook white-collar crime allegations. To see what the fuss is all about, feel free to look into this video Kristen Shaughnessy shared on Twitter.

A lot of the commotion is around stock manipulation and malpractice by notable hedge funds. One user, BigC commented on the post above, “$40BB shock to the system. At what point does Jefferies realize they aren’t stopping the $FNGR deluge & mitigate losses? Or do they just roll over & become a Melvin Capital & let themselves implode? Unlike Melvin-there won’t be any Citadel to write them a $10BB check”.

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To better your understanding of fundamental tactics, we’ve provided a brief overview below. Naturally, no investor tolerates manipulation. The AMC and GME events were an initial testament to the strength of retail investors and their determination to resist such actions. Although early stage, it appears FingerMotion is following a similar trend, and more hedge funds could be in for a rude awakening as more investors join in on the retail army.  

The SEC on its way to protect retail investors
byu/Ren3666 inwallstreetbets

Before we jump into the tactics, it’s important to note that HAMShortkiller also shared a post about previous malpractice back in 2009, which highlights the story behind Rocker Partners and Overstock.com (NASDAQ: OSTK). There’s an important Vimeo at the bottom of the article, explaining all the major details of what happened and how these practices work. While this article is from over a decade ago, the user suggests some of the exact same practices are happening today with FingerMotion. Practices such as a “Bear raid“.

Exploring Stock Manipulation Tactics:

Hedge funds have a bag full of short shares at their disposal, letting them play with a stock’s price using tactics like short-ladder attacks. They go heavy on borrowed shares to bet against stocks, especially when the demand is high, stirring the stock prices. Strangely, these moves aren’t illegal or firmly tackled by the SEC yet, raising eyebrows on their potential manipulation.

Bear Raid:

Short sellers can strategically utilize both traditional media and online discussion platforms to spread negative narratives about the target company. Through leaked information to journalists, bloggers, and discussion boards, they aim to create a broad negative image.

This orchestrated use of media is geared towards sowing doubt and fear among investors, employing sensational headlines, speculative reports, and exaggerated claims to induce panic selling and drive down the stock price.

Social media platforms play a crucial role in rapidly amplifying these negative narratives. Short sellers and their networks leverage these channels to spread rumors, creating a chain reaction of panic selling and significant stock price volatility.

The collaboration between short sellers and the media seeks to fulfill a prophecy of fear, prompting sell-offs that benefit the short sellers. It’s essential for investors to critically evaluate information, considering multiple reliable sources, and to be discerning of sensationalized narratives, particularly those propagated on online discussion platforms. Verifying information from credible sources is vital to avoid falling prey to orchestrated attempts to manipulate stock prices for personal gain.

Off Exchange Trading:

Hedge funds and market makers engage in off-exchange trading, allowing them to trade and swap stocks on foreign exchanges without the need for price disclosure. This practice involves manipulating the circulating supply by not accurately reporting transactions, a significant challenge the SEC is working to tackle. Despite efforts to introduce D-Limit orders for enhanced transparency, hedge funds and market makers present resistance.

Naked Shorting:

Stocks like $AMC and $GameStop have experienced an abundance of failure-to-deliver (FTD) orders, often a result of ‘short parties’ lacking the underlying asset. Retail investors have highlighted the presence of synthetic shares, known as naked shares, in the market. Naked shorting, though made illegal after the 2008–09 financial crisis, persists due to regulatory gaps and discrepancies between trading systems. The mainstream exposure of this practice raises concerns, emphasizing the need for retail investors to address these issues with the SEC.

A Community Against Market Manipulation:

We’re continuing to see efforts to expose malpractices in the stock market. Community members like HAMShortkiller are all over social media, shedding light on manipulation tactics driven by hedge fund partners. It’s refreshing to see investors sharing factual and positive articles regarding a stock’s performance or analytics. It’s clear the investing community aims to stay informed and united against market manipulation once and for all. 

The latest movie release, “DumbMoney” is a great example of the hysteria that occured a short time ago, but some claim it’s only the beginning. According to Stephmase22 off Twitter, nothing has changed to prevent the same kind of market manipulation that happened with AMC and GME. She’s insinuating the same kind of manipulation is happening here with FNGR and that it must be stopped.

The general idea is that if the SEC won’t take action, then the folks who are getting the short end of the stick will step up, by short squeezing the players behind the manipulation.

We will update you on FNGR when more details emerge, subscribe to Microcapdaily to follow along!

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Disclosure: We have not been compensated for this article/video. MicroCap Daily is not an investment advisor; this article/video does not provide investment advice. Always do your research, make your own investment decisions, or consult with your nearest financial advisor. This article/video is not a solicitation or recommendation to buy, sell, or hold securities. This article/video is our opinion, is meant for informational and educational purposes only, and does not provide investment advice. Past performance is not indicative of future performance.

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