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Thursday, October 21, 2021

Two Therapeutic Platforms; Enzolytics Inc (OTCMKTS: ENZC); BioClonetics Engineering Targeted Monoclonal Antibodies

Enzolytics Inc (OTCMKTS: ENZC) is among the most exciting stocks in small caps recently skyrocketing to highs of $0.1176 as the Company consummated its merger with BioClonetics on December 1; World AIDS Day. Enzolytics reported it executed a definitive business combination agreement successfully merging the biotech companies. Through a merger of biotech companies, Enzolytics now advances two separate but complementary therapy platforms for treating infectious diseases, targeting HIV and the CoronaVirus.

Additionally, the Company has identified correlative structure between the HIV virus and the CoronaVirus and, with its capability to produce targeted monoclonal antibodies, is moving forward to produce monoclonal antibodies targeting the CoronaVirus. The Company is extending its lab capabilities on the Texas A&M University campus at the Institute for Pre-clinical Studies, where it will be producing both addition monoclonal antibodies against HIV and the against the CoronaVirus.

Enzolytics Inc (OTCMKTS: ENZC) is a drug development company committed to the commercialization of its proprietary proteins for the treatment of debilitating infectious diseases. Enzolytics is committed to creating drugs for the better health of mankind. Enzolytics is a 49% shareholder of IMMB BG. Enzolytics’ flagship compound, ITV-1 (Immune Therapeutic Vaccine-1), is a suspension of Inactivated Pepsin Fraction (IPF), which studies have shown is effective in the treatment of HIV/AIDS. IPF is the active drug substance of ITV-1 and is a purified extract of porcine pepsin. ITV-1 has been shown to modulate the immune system.

The Company has merged with BioClonetics Immunotherapeutics, Inc. is a Dallas, Texas biotech company with proprietary technology for producing fully human monoclonal antibodies (mAbs) against infectious diseases including HIV, rabies, influenza A, influenza B, tetanus, and diphtheria. Its proprietary methodology for produce fully human monoclonal antibodies may be used to produce therapeutics treatments for name infectious diseases, including the Coronavirus.

The merger was consummated on December 1; Enzolytics reported it executed a definitive business combination agreement successfully merging the biotech companies Enzolytics, Inc. and BioClonetics Immunotherapeutics, Inc. on World AIDS Day. Through a merger of biotech companies, Enzolytics now advances two separate but complementary therapy platforms for treating infectious diseases, targeting HIV and the CoronaVirus.

ITV-1, invented by Harry Zhabilov, the CSO of the Company, is a patented antiviral peptide that has been tested in clinical studies at the National Center of Infectious and Parasitic Diseases in Bulgaria. In these trials ITV-1, demonstrated effectiveness in the treatment of HIV patients in various stages of the disease. In trials conducted in 31 patients, the therapeutic showed efficacy, with 68% of those individuals tested experiencing an increase in CD4 + T lymphocytes. This increase was accompanied by an increase in the CD4/CD8 index and CD4% in over 50% of those tested. The increase in these parameters demonstrated statistical significance compared to the control group. The absolute number and the relative percent of CD8 + T lymphocytes were also decreased. And the viral load in 80.5% of those tested was below the threshold of detection. This Enzolytics anti-HIV treatment is now being advanced through the certification stage to thereafter be made available for patient therapy.

The Company is now combining this technology with recently acquired technology for creating fully human anti-monoclonal antibodies for treating HIV. From this technology created by BioClonetics, the Company has a fully human anti-monoclonal antibody that has been tested in 5 international labs where it neutralized over 95% of all strains of the HIV virus against which it was tested. Multiple recombinant forms of this parent antibody are now being produced, and additional neutralizing antibodies are being created to provide combined monoclonal antibody therapies for patients with HIV.

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ENZCThe Company has recently confirmed plans to test its monoclonal antibodies at the University of Strasbourg, France, under the direction of Dr. Christiane Moog, Ph.D., Research Director at INSERM, University of Strasbourg, a leading specialist in conducting the preferred PBMC based in vitro neutralization assays protocol for anti-HIV monoclonal antibodies. Additional testing of the Company’s antibodies is also being planned at San Raffaele Scientific Institute, Milan, Italy, under the direction of a further expert in the field, Dr. Gabriella Scarlatti, M.D., Ph.D., Head of Viral Evolution and Transmission Unit at San Raffaele Scientific Institute. The therapies of Enzolytics’ two technologies, that produced by Enzolytics and that created by BioClonetics will be tested in combination and are expected to be synergistic.

Additionally, the Company has identified correlative structure between the HIV virus and the CoronaVirus and, with its capability to produce targeted monoclonal antibodies, is moving forward to produce monoclonal antibodies targeting the CoronaVirus. The Company is extending its lab capabilities on the Texas A&M University campus at the Institute for Pre-clinical Studies, where it will be producing both addition monoclonal antibodies against HIV and the against the CoronaVirus.

The Company’s addition of Dr. Ronald Moss, MD, to its Medical Advisory Board has provided experienced guidance for its strategies and in its planned testing and validation of its therapeutics in animal and clinical trials.

Charles Cotropia, CEO of Enzolytics stated: “The current antiretroviral therapy for HIV/AIDS is not a cure, and the side effects from lifelong use are significant. Also, the yearly average cost of treatment on anti-retroviral is $14,000 to $20,000 per year, and the average lifetime cost is calculated as $379,000. The cost of an anti-HIV therapy we propose would be a fraction of these costs as the treatment would be for a limited time and not require life-long use. Just as monoclonal antibodies were available to President Trump when he contracted the Coronavirus, monoclonal antibodies can be made available to treat HIV patients, and we believe we are on the verge of providing such a therapy.”

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ENCZ is among the most exciting stocks in small caps recently skyrocketing to highs of $0.1176 as the Company consummated its merger with BioClonetics on December 1; World AIDS Day. Enzolytics reported it executed a definitive business combination agreement successfully merging the biotech companies. Through a merger of biotech companies, Enzolytics now advances two separate but complementary therapy platforms for treating infectious diseases, targeting HIV and the CoronaVirus. Additionally, the Company has identified correlative structure between the HIV virus and the CoronaVirus and, with its capability to produce targeted monoclonal antibodies, is moving forward to produce monoclonal antibodies targeting the CoronaVirus. The Company is extending its lab capabilities on the Texas A&M University campus at the Institute for Pre-clinical Studies, where it will be producing both addition monoclonal antibodies against HIV and the against the CoronaVirus. We will be updating on ENZC when more details emerge so make sure you are subscribed to Microcapdaily so you know what’s going on with ENZC.

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Disclosure: we hold no position in ENZC either long or short and we have not been compensated for this article

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